Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

177
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
177

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanical Taming of Hardy-Cope Rearrangements.

ACS central science·2026
Same author

Three-dimensional structure of the palbociclib-HIV TAR complex.

Nucleic acids research·2026
Same author

The kinase inhibitor palbociclib binds to HIV TAR RNA with very low nanomolar affinity and exquisite specificity.

Nucleic acids research·2026
Same author

Sensitized Disequilibration of Water-Soluble Azopolymers.

Angewandte Chemie (International ed. in English)·2025
Same author

Azobenzene-Attached (NHC)Gold(I) and (NHC)Copper(I) Complexes as Photoswitchable Catalysts.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024
Same author

Structure of Essential RNA Regulatory Elements in the West Nile Virus 3'-Terminal Stem Loop.

Journal of molecular biology·2024

Related Experiment Video

Updated: May 1, 2026

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms
08:28

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

1.9K

Nanoporous frameworks exhibiting multiple stimuli responsiveness.

Pintu K Kundu1, Gregory L Olsen2, Vladimir Kiss3

  • 1Department of Organic Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.

Nature Communications
|April 9, 2014
PubMed
Summary

Responsive nanoporous frameworks were created by incorporating spiropyran molecular switches. These materials show reversible color changes and controlled metal ion capture/release, opening new application possibilities.

More Related Videos

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.9K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.9K

Related Experiment Videos

Last Updated: May 1, 2026

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms
08:28

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

1.9K
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.9K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.9K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Nanotechnology

Background:

  • Nanoporous frameworks offer unique properties for applications like gas storage and catalysis.
  • Responsive materials that change properties with external stimuli are highly sought after.
  • Immobilizing molecular switches within nanopores is a strategy to create stimuli-responsive materials.

Purpose of the Study:

  • To develop novel nanoporous frameworks incorporating molecular switches.
  • To investigate the stimuli-responsive behavior of these new materials.
  • To explore potential applications in controlled capture and release.

Main Methods:

  • Synthesis of two families of nanoporous materials.
  • Incorporation of spiropyran molecular switches into the framework structure.
  • Characterization of material properties including photochromism, acidochromism, and metal ion interactions.

Main Results:

  • The synthesized materials exhibit reversible photochromism and acidochromism without solvents.
  • Light-induced capture and release of metal ions were demonstrated.
  • Reversible chromism was observed upon solvation and desolvation processes.

Conclusions:

  • Nanoporous frameworks functionalized with spiropyran switches can be reversibly controlled by external stimuli.
  • These materials show promise for applications requiring light- or acid-triggered responses.
  • The ability to manipulate properties like metal ion binding offers new avenues for smart material design.