Related Experiment Video
Updated: May 1, 2026
In Vitro and In Vivo Approaches to Determine Intestinal Epithelial Cell Permeability
Published on: October 19, 2018
Ex vivo clinical measurement of the optical penetration depth in digestive tissues
1Gastoenterology Unit, Centre Hospitalier Notre-Dame et Reine Fabiola, Charleroi, Belgium, BE.
Abstract:
The optical penetration depth of 120 biopsy samples taken from normal or neoplastic digestive tissues is measured by means of a device which can be used in a clinical environment, is easy to handle and delivers results quickly. It is seen that, at 655 nm, values of the penetration depth are centred around 1.1 mm and that they can vary by roughly a factor of 2 between samples of a given kind of tissue. This latter result suggests performing individual measurements immediately before carrying out photodynamic therapy.
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