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Activation of a GPCR leads to eIF4G phosphorylation at the 5' cap and to IRES-dependent translation

Kelly León1, Thomas Boulo1, Astrid Musnier1

  • 1UMR85Unité Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, FranceGroup «Biology and Bioinformatics of Signaling Systems (BIOS)»CNRS, UMR7247, F-37380 Nouzilly, FranceUniversité François RabelaisF-37041 Tours, FranceIFCEF-37380 Nouzilly, FranceUniversité Pierre et Marie CurieUniversity of Paris VI, CNRS, UMR 7150 Mer et Santé, Equipe Traduction, Cycle Cellulaire, et Développement, Station Biologique de Roscoff, F-29239 Roscoff, FranceUniversité Européenne de BretagneF-29239 Roscoff, FranceBioinformatics GroupDepartment of Computer Science, University of Freiburg, Freiburg, GermanyUMR85Unité Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, FranceGroup «Biology and Bioinformatics of Signaling Systems (BIOS)»CNRS, UMR7247, F-37380 Nouzilly, FranceUniversité François RabelaisF-37041 Tours, FranceIFCEF-37380 Nouzilly, FranceUniversité Pierre et Marie CurieUniversity of Paris VI, CNRS, UMR 7150 Mer et Santé, Equipe Traduction, Cycle Cellulaire, et Développement, Station Biologique de Roscoff, F-29239 Roscoff, FranceUniversité Européenne de BretagneF-29239 Roscoff, FranceBioinformatics GroupDepartment of Computer Science, University of Freiburg, Freiburg, GermanyUMR85Unité Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, FranceGroup «Biology and Bioinformatics of Signaling Systems (BIOS)»CNRS, UMR7247, F-37380 Nouzilly, FranceUniversité François RabelaisF-37041 Tours, FranceIFCEF-37380 Nouzilly, FranceUniversité Pierre et Marie CurieUniversity of Paris VI, CNRS, UMR 7150 Mer et Santé, Equipe Traduction, Cycle Cellulaire, et Développement, Station Biologique de Roscoff, F-29239 Roscoff, FranceUniversité Européenne de BretagneF-29239 Roscoff, FranceBioinformatics GroupDepartment of Computer Science, University of Freiburg, Freiburg, GermanyUMR85Unité Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, FranceGroup «Biology and Bioinformatics of Signaling System

Journal of Molecular Endocrinology
|April 9, 2014
PubMed

Keywords:
FSHGPCRHEK293 cellsIRESeIF4GmRNA translation

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