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Updated: May 1, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis and risk of venous thromboembolism: a systematic review and meta-analysis
Patompong Ungprasert1, Anawin Sanguankeo2, Sikarin Upala2
1From the Department of Medicine, Faculty of Medicine Siriraj Hospital, Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang road, Bangkok, 10700, Thailand and Department of Cardiology, University of Utah, School of Medicine, 30 N 1900 E, Salt Lake City, Utah, 84132, USA patompong.ungprasert@bassett.org.
Background:
Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, have been shown to increase venous thromboembolism (VTE) risk but the data on psoriasis is unclear.
Methods:
We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio or standardized incidence ratio comparing VTE risk in patients with psoriasis vs. non-psoriasis participants. Pooled risk ratio and 95% confidence intervals were calculated using a random effect, generic inverse variance method.
Result:
Four studies were identified and included in our data analysis. The pooled risk ratio of VTE in patients with psoriasis was 1.46 (95% CI, 1.29-1.66). The statistical heterogeneity of this meta-analysis was high with an I(2) of 86%.
Conclusion:
Our study demonstrated a statistically significant increased VTE risk among patients with psoriasis.
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