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Erectile dysfunction and central obesity: an Italian perspective.
Giovanni Corona, Giulia Rastrelli, Sandra Filippi
1Sexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy.
Asian Journal of Andrology
|April 10, 2014
Summary
Obesity, especially central obesity, is linked to erectile dysfunction (ED) and lower testosterone. Addressing ED in obese individuals can motivate lifestyle changes for improved overall health.
Area of Science:
- Endocrinology
- Urology
- Cardiovascular Medicine
Background:
- Erectile dysfunction (ED) is a common comorbidity in obese individuals.
- Central obesity is specifically linked to arteriogenic ED and hypogonadism.
Purpose of the Study:
- To critically analyze the relationship between obesity and ED.
- To dissect the connections between these two pathological conditions.
Main Methods:
- Review of current clinical and preclinical evidence.
- Analysis of the association between visceral fat accumulation and ED, independent of comorbidities.
Main Results:
- Obesity, particularly central obesity, correlates with arteriogenic ED and reduced testosterone levels.
- Psychological factors appear to play a minor role in obesity-related ED.
- The mechanism by which visceral fat impairs penile microcirculation remains unclear.
Conclusions:
- Obesity-associated hypogonadism and cardiovascular risk may contribute to ED prevalence.
- ED in obese patients can serve as a motivator for lifestyle modification and treatment of underlying conditions.
- Addressing ED can lead to improved overall health in obese individuals.
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