Related Experiment Video
Updated: May 1, 2026

10:37
Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
7.4K
Spirocheatal shock syndrome.
A A Alfaifi, I Masoodi1, O Alzaidi
1Department of Gastroenterology, FACP College of Medicine and medical sciences, Taif University, Taif, Saudi Arabia.
Indian Journal of Medical Microbiology
|April 10, 2014
Summary
A homeless man presented with fever, jaundice, and multi-organ dysfunction. He was diagnosed with Borrelia recurrentis, highlighting the need for vigilance in non-endemic areas.
Area of Science:
- Infectious Diseases
- Internal Medicine
- Clinical Case Study
Background:
- Borrelia recurrentis infection, commonly known as relapsing fever, is a tick-borne illness.
- While endemic in certain regions, its occurrence in non-endemic areas necessitates heightened clinical suspicion.
Observation:
- A 30-year-old homeless male presented with high-grade fever, jaundice, hypotension, and multi-organ dysfunction syndrome.
- Initial investigations revealed no radiological evidence of biliary obstruction.
- The patient was brought from the street by emergency medical services.
Findings:
- The patient was diagnosed with Borrelia recurrentis infection after initial resuscitation.
- Despite a challenging clinical course during hospitalization, the patient showed improvement.
- The patient was discharged in a stable condition after 20 days.
Implications:
- This case highlights the importance of considering Borrelia recurrentis in patients presenting with severe febrile illness and multi-organ dysfunction, even outside typical endemic zones.
- Clinicians should maintain a high index of suspicion for rare infectious diseases in diverse patient populations.
- Prompt diagnosis and management are crucial for favorable outcomes in Borrelia recurrentis cases.
Related Concept Videos
Bacterial Phylum Spirochaetes
1.5K
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
1.5K
Other Stress Responses in Bacteria
587
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
587
Bacterial Phylum Tenericutes
673
The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
673
Staphylococcal Skin Infections
143
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
143
Bacterial Meningitis II: Pathophysiology
24
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
24
Gene Regulation During Sporulation
713
Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
713

