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Updated: May 1, 2026

Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
Inflammatory bowel disease in Jamaica
Kerry A Penn1, Dwight O Whittle1, Michael G Lee1
1Department of Medicine, The University of the West Indies, Jamaica.
Inflammatory bowel disease (IBD) is uncommon in Jamaica, with ulcerative colitis more prevalent than Crohn's disease. Clinical features and outcomes in Jamaican patients align with global findings for IBD.
Area of Science:
- Gastroenterology
- Epidemiology
- Internal Medicine
Background:
- Inflammatory bowel disease (IBD) is predominantly observed in developed nations, with limited data on Caucasian populations.
- This study investigates IBD prevalence and characteristics in a Caribbean population.
Purpose of the Study:
- To describe the epidemiology and clinical presentation of inflammatory bowel disease (IBD) in Jamaica.
- To compare findings with international IBD literature.
Main Methods:
- A retrospective review of all IBD patients at the University Hospital of the West Indies, Jamaica, from January 2000 to January 2010.
- Data collection included patient demographics, disease type, clinical features, and extraintestinal manifestations.
Main Results:
- 103 IBD patients were identified: 64 with ulcerative colitis (UC) and 39 with Crohn's disease (CD).
- The most common presenting symptoms were diarrhea (93%) and rectal bleeding (56%). Extraintestinal manifestations occurred in 38% of patients.
- CD predominantly presented as colitis only (56%), while UC frequently involved left-sided disease (44%).
Conclusions:
- IBD is relatively uncommon in Jamaica, with UC being more frequent than CD.
- The clinical presentation and outcomes of IBD in Jamaica are comparable to those reported in other global studies.
- Further research into IBD in diverse populations is warranted.
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