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Flow cytometric analysis of lymphomas.

R C Braylan¹, N A Benson

¹Department of Pathology, University of Florida College of Medicine, Gainesville 32610.

Archives of Pathology & Laboratory Medicine

|June 1, 1989

Summary

Flow cytometry is a key tool for characterizing lymphomas by analyzing cell surface antigens and DNA content. This method aids in the diagnosis and classification of these lymphoid diseases.

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Area of Science:

Hematology
Immunology
Cell Biology

Background:

Flow cytometry is increasingly utilized for lymphoma characterization.
Analysis of cell surface antigens and DNA content offers valuable biological insights.

Purpose of the Study:

To provide practical guidance on using flow cytometry for lymphoma evaluation.
To discuss the application, benefits, and drawbacks of flow cytometry in diagnosing and classifying neoplastic lymphoid diseases.

Main Methods:

Handling, preparation, and staining of lymphoid samples for flow cytometry.
Data analysis and interpretation strategies for flow cytometry results.

Main Results:

Flow cytometry provides crucial data for lymphoma diagnosis and classification.
The technique offers advantages in evaluating neoplastic lymphoid diseases.

Conclusions:

Flow cytometry is an essential technique in the characterization of lymphomas.
Understanding practical aspects and data interpretation is key to its effective use in clinical practice.

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