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Interstitial Keratitis, Vertigo, and Vasculitis: Typical Cogan's Syndrome
Ahad Azami1, Nasrollah Maleki1, Mohammadreza Kalantar Hormozi2
1Department of Internal Medicine, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil, Iran.
Case Reports in Medicine
|April 10, 2014
Summary
This case study highlights Cogan
Area of Science:
- Ophthalmology
- Rheumatology
- Neurology
Background:
- Cogan's syndrome (CS) is a rare chronic inflammatory disorder.
- It typically affects young adults with characteristic eye and ear symptoms.
- CS can be associated with systemic vasculitis and aortitis.
Purpose of the Study:
- To describe a classic case of Cogan's syndrome.
- To illustrate the diagnostic challenges and treatment approach.
Main Methods:
- Case report of a 47-year-old female presenting with diverse symptoms.
- Ophthalmologic examination including slit lamp.
- Audiologic tests: Pure Tone Audiogram (PTA) and Auditory Brainstem Response (ABR).
Main Results:
- The patient presented with bilateral interstitial keratitis, sensorineural hearing loss, and other systemic symptoms.
- Diagnostic criteria for Cogan's syndrome were met.
- Differential diagnoses were excluded.
Conclusions:
- Early diagnosis and prompt treatment of Cogan's syndrome are crucial.
- Combination therapy with corticosteroids and cyclophosphamide showed partial improvement.
- This case underscores the importance of recognizing CS in adults presenting with ocular and audiovestibular deficits.
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