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Updated: May 1, 2026

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
Published on: April 10, 2019
Spontaneous intestinal perforation: an atypical presentation of neutropenic enterocolitis-a case report
Aylin Canbolat Ayhan1, Cetin Timur1, Ersin Bocu1
1Pediatric Hematology-Oncology Department, Goztepe Education and Research Hospital, Istanbul Medeniyet University, 34722 Istanbul, Turkey.
Abstract:
Background. Neutropenic enterocolitis is one of the most common gastrointestinal complications seen in patients who are receiving chemotherapy for leukemia. Severe neutropenia is the main underlying factor of this pathology. It is characterized by fever and abdominal pain. Case Presentation. Herein, we report a case of neutropenic enterocolitis which presented with intestinal perforation in an afebrile patient who was diagnosed with acute lymphoblastic leukemia and was receiving induction chemotherapy. Conclusion. We aimed to emphasize the importance of enterocolitis and increase awareness against such severe complications which could have unexpected presentations.
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