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Published on: August 11, 2023
Recurrent Transient Ischemic Attacks in a Patient with POEMS Syndrome
A Akyol1, B Nazliel1, H Z Batur Caglayan1
1Department of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, Turkey.
Abstract:
A 47-year-old female with a prior history of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome was admitted with transient ischemic attacks complicated by dysarthria and right-sided hemiparesis. A blood survey indicated thrombocytosis and hyperfibrinogenemia while imaging of intracranial vasculature showed occlusion of the bilateral middle cerebral arteries. POEMS syndrome, of which arterial thromboses have been mentioned as a manifestation, is rarely accompanied by transient ischemic attacks. The pathophysiologic mechanism is yet unclear and needs further investigation.
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