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Updated: May 1, 2026
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Basaloid squamous cell carcinoma in the nasal cavity treated with proton beam therapy concurrent with cisplatin: a
Shigeyuki Takamatsu1, Kazutaka Yamamoto, Tamaki Kondou
1Proton Therapy Center, Fukui Prefectural Hospital, 2-8-1 Yotsui, Fukui City, Fukui 910-8526, Japan. shigerad@staff.kanazawa-u.ac.jp.
Introduction:
Basaloid squamous cell carcinoma is a rare and aggressive variant of squamous cell carcinoma. Basaloid squamous cell carcinoma is mostly seen in the upper aerodigestive tract and has a propensity for lymph node spread and systemic metastases. Various treatment modalities have been reported, including surgical excision supplemented with radiotherapy/adjuvant chemotherapy. To the best of our knowledge, treatment of nasal basaloid squamous cell carcinoma with proton beam therapy and cisplatin has not been described in the literature.
Case Presentation:
We report the case of a 56-year-old Japanese man with locally invasive basaloid squamous cell carcinoma in his right nasal cavity with invasion of the orbit, paranasal sinus, and buccal subcutaneous tissue. He underwent proton beam therapy concurrent with cisplatin. Acute and late side effects did not exceed grade 3. At 24-month follow up, he remains in complete remission.
Conclusion:
Proton beam therapy concurrent with cisplatin may be one choice for locally invasive basaloid squamous cell carcinoma.
