Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Toluene embryopathy: two new cases.

J H Hersh1

  • 1Department of Pediatrics, University of Louisville, Kentucky 40202.

Journal of Medical Genetics
|May 1, 1989
PubMed
Summary
This summary is machine-generated.

Toluene embryopathy, a condition affecting fetal development, is characterized by microcephaly and central nervous system issues. This highlights toluene

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expansion and further delineation of the SETD5 phenotype leading to global developmental delay, variable dysmorphic features, and reduced penetrance.

Clinical genetics·2017
Same author

20p11 deletion in a female child with panhypopituitarism, cleft lip and palate, dysmorphic facial features, global developmental delay and seizure disorder.

American journal of medical genetics. Part A·2011
Same author

Hypertrophy of the masseter muscle.

Archives of otolaryngology·2010
Same author

Plastic repair of a large alveolar-antral fistula.

Archives of otolaryngology·2010
Same author

Some present-day concepts of headache; an analysis of 1,000 cases of headache.

The Annals of otology, rhinology, and laryngology·2010
Same author

Identification of a previously unrecognized microdeletion syndrome of 16q11.2q12.2.

Clinical genetics·2008
Same journal

Longest surviving patient with a homozygous splice-altering <i>EGFR</i> pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.

Journal of medical genetics·2026
Same journal

Functional characterisation and pathological significance of variants of <i>MEF2C</i> promoter in tetralogy of Fallot.

Journal of medical genetics·2026
Same journal

Identification of biallelic loss-of-function <i>PREP</i> variants in three individuals with syndromic intellectual disability.

Journal of medical genetics·2026
Same journal

Inherited retinal disease genes with dual inheritance patterns: insights from the IRD-PT registry.

Journal of medical genetics·2026
Same journal

Interpreting <i>TP53</i> variants: somatic mosaicism and <i>ERCC6L2</i>-driven clonal evolution.

Journal of medical genetics·2026
Same journal

Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome.

Journal of medical genetics·2026
See all related articles

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Toxicology

Background:

  • Toluene exposure during pregnancy is a known risk factor for adverse developmental outcomes.
  • Previous reports have documented cases of toluene embryopathy.

Observation:

  • Two additional cases of toluene embryopathy are presented.
  • These cases involve children born to mothers with regular toluene inhalation during gestation.

Findings:

  • Toluene embryopathy presents with microcephaly, CNS dysfunction, attentional deficits, hyperactivity, developmental delays (especially language), minor anomalies, and growth deficiency.
  • The findings reinforce toluene's role as a significant human teratogen.

Implications:

  • Increased awareness of toluene's teratogenic potential is crucial for prenatal care.

Related Experiment Videos

  • Further research into the mechanisms and long-term effects of toluene exposure is warranted.