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Clinical performance of Roche Cobas 4800 HPV Test
Miao Cui1, Nicholas Chan1, Momo Liu1
1Department of Pathology, Mount Sinai School of Medicine, New York, New York, USA.
Journal of Clinical Microbiology
|April 11, 2014
Abstract:
Evaluation of the Cobas 4800 test demonstrated that Cobas had a low rate of cross-reactivity with low-risk human papillomavirus (lrHPV), a 3.74% disconcordance rate between prealiquots and postaliquots, and failure rates of 4.57% and 1.16%, respectively, after vortexing and swirling. This study demonstrated that the Cobas test has good sensitivity, accuracy, and reproducibility for detecting 14 high-risk HPV (hrHPV) genotypes.
