Related Experiment Video
Updated: May 1, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Gas gangrene in the diabetic foot: lessons learned from a salvaged limb
Abstract:
A 55 year old man was seen in the emergency department with an infected right foot and sepsis. Examination of the right foot revealed subcutaneous crepitus from the metatarsal head up to the tarsus; interstitial and intramedullary gas was confirmed on x-rays and computed tomographic scans. During 44 days of hospitalization, the patient was treated with multiple courses of antibiotic therapy, various wound care modalities (including negative wound pressure therapy) and several surgical interventions (debridements, amputations, revascularizations and reconstructive plastic surgery). Although limb salvage was ultimately accomplished, in retrospect many management decisions were suboptimal. A critical reassessment of our approach to this patient allowed us to identify several areas for improvement and this audit provided us an opportunity to learn from managing this difficult case.
Related Concept Videos
Diabetic Foot Ulcer
Peripheral Artery Disease V: Postoperative Nursing Management
Diabetic Neuropathy
Peripheral Artery Disease IV: Nursing Management
Complications of Diabetes Mellitus
Peripheral Artery Disease III: Interprofessional Care

