Related Experiment Video
Updated: May 1, 2026

A Bilingual Computational Workflow for Identifying Potential PLK1 Inhibitors in American Sign Language and English
Published on: April 3, 2026
[Simplification of biotic ligand model and evaluation of predicted results]
Abstract:
The prediction accuracy of LC50 on four species (Fathead minnow, D. magna, D. pulex, Rainbow trout) was 0. 075, 0. 52, 0.96 and 0.29 respectively as determined by their onserved values of LC50 in surface water. Predicted results indicated that the correlation between forecast error and LA50 was exponential. The accuracy of Fathead minnow and Rainbow trout became 0.59 and 0.42 after adjusting LA50. The correlation between hardness and LA50 showed that the prediction effectiveness of BLM was poor in soft water. In addition, four important parameters (DOC, pH values, the concentration of HCO3-, temperature) were selected to build the multiple linear relationship with LC50 by applying 500 groups of random uniform water quality parameter in BLM. Biotic ligand model was effectively simplified.
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