[Diagnosis and treatment of solid-pseudopapillary carcinoma of the pancreas]

To summarize the institutional experiences of diagnosis, treatment and prognosis for solid-pseudopapillary carcinoma of the pancreas (SPCP).

Retrospective analyses were performed for 11 cases of SPCP diagnosed in recent 15 years at Department of Abdominal Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences.

There were 10 females and 1 male with an average age of 33 years. The locations included head (n = 7) and body and tail (n = 4).Five of them had pain in abdomen or back while another 6 were found accidentally. Their images were of solid-cystic tumors and all serum markers stayed within a normal range. All received en bloc resection. The average maximum diameter was 6 cm and the percentage of patients with lymph node metastases was 36.4% (4/11). Their average follow-up period was 80.5 months. Two patients died postoperatively from hepatic metastases. And another 9 survived without relapse or metastasis.

As one of rare pancreatic neoplasms with non-specific clinical characteristics, SPCP primarily affects young females. A definite diagnosis depends on pathological confirmation.Surgery is the first-choice treatment with a favorable prognosis.Radical resection with R0 margin is crucial to long-term postoperative survival.