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Published on: December 9, 2015
Review: higher vitamin D status and supplementation may be associated with risks
Kaveri Korgavkar1, Michael Xiong1, Martin A Weinstock2
1Dermatoepidemiology Unit, VA Medical Center, 830 Chalkstone Avenue, 514, Providence, Rhode Island 02908, USA, Department of Dermatology.
Abstract:
The prevalence of low vitamin D levels and associated risks has led to an increase in supplementation. However, a "U-shaped" relationship has been suggested between vitamin D status and adverse effects, with risks observed both in low and high levels. While risks associated with low levels of vitamin D have been extensively studied, the risks of higher levels of vitamin D have not been as widely circulated. We sought to describe key observed adverse risks with vitamin D supplementation and higher serum 25(OH)-D levels in healthy adult populations.
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