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Ag-NOR staining in the Bennett wallaby, Macropus rufogriseus: evidence for dosage compensation
M K Dhaliwal1, S Pathak, L R Shirley
1Department of Cell Biology, University of Texas, M. D. Anderson Cancer Center, Houston 77030.
Abstract:
Silver staining of cells in metaphase and interphase nuclei of both sexes of the Bennett wallaby, Macropus rufogriseus, has shown that (1) the nucleolus organizer region (NOR) is located only on the X chromosome (single Ag-NOR); (2) both X chromosomes in the female cells stain with silver; (3) the amounts of silver staining of metaphase chromosomes and interphase nuclei of both sexes are very similar; (4) the single X chromosome is hyperactive in male cells to equalize the expression of rRNA genes in the female cells with two X chromosomes; and (5) the mechanism of dosage compensation for rRNA genes in this species is similar to that reported for Drosophila salivary gland cells.