[A case of Pelger-Huet anomaly in a premature infant]

The report deals with a prematurely born child affected with multilateral anomalies of body development, defect of cell immunity and acquired Pelger-Huët's anomaly. Pelger-Huët's anomaly was detected in a blood smear during the third week of life by an extreme deviation to the left, the degree of which fluctuated, however, depending on the reiterating exacerbations of the infect. The morphological changes of blood elements persisted until exitus letalis in a severe respiratory infect. The changes of the karyotype and possible relations to Pelger-Huët's anomaly and malformations of development are discussed in detail.