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Updated: May 1, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Post-contrast T1-weighted sequences in pediatric abdominal imaging: comparative analysis of three different sequences
Andreia Roque1, Miguel Ramalho, Mamdoh AlObaidy
1Department of Radiology, University of North Carolina at Chapel Hill, CB 7510 - 2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
Insights
Radial 3-D-GRE imaging offers superior image quality in pediatric abdominopelvic MRI compared to standard 3-D-GRE and MP-GRE techniques. This method minimizes respiratory motion artifacts in young children.
Area of Science:
- Radiology
- Medical Imaging
- Pediatric Imaging
Background:
- Post-contrast T1-weighted imaging is crucial for pediatric abdominopelvic MRI.
- Respiratory motion in sedated children significantly degrades image quality.
Purpose of the Study:
- To compare image quality of three post-contrast T1-weighted MRI techniques.
- Evaluate standard 3-D-GRE, MP-GRE, and radial 3-D-GRE in children under 5.
Main Methods:
- Sixty MRI exams in 51 pediatric patients (mean age 2.5 years) were analyzed.
- Two independent reviewers assessed image quality and artifacts.
- Scans were performed at 1.5 T and 3 T.
Main Results:
- Radial 3-D-GRE and MP-GRE showed significantly less respiratory motion.
- Standard 3-D-GRE had the lowest scores for edge definition, vessel clarity, and overall quality.
- Radial 3-D-GRE achieved the highest overall image quality ratings.
Conclusions:
- Fat-suppressed radial 3-D-GRE is the preferred post-contrast T1-weighted technique for pediatric abdominopelvic MRI in patients under 5 years.
- This technique is optimal when dynamic imaging is not required.
Background:
Post-contrast T1-weighted imaging is an essential component of a comprehensive pediatric abdominopelvic MR examination. However, consistent good image quality is challenging, as respiratory motion in sedated children can substantially degrade the image quality.
Objective:
To compare the image quality of three different post-contrast T1-weighted imaging techniques-standard three-dimensional gradient-echo (3-D-GRE), magnetization-prepared gradient-recall echo (MP-GRE) and 3-D-GRE with radial data sampling (radial 3-D-GRE)-acquired in pediatric patients younger than 5 years of age.
Materials And Methods:
Sixty consecutive exams performed in 51 patients (23 females, 28 males; mean age 2.5 ± 1.4 years) constituted the final study population. Thirty-nine scans were performed at 3 T and 21 scans were performed at 1.5 T. Two different reviewers independently and blindly qualitatively evaluated all sequences to determine image quality and extent of artifacts.
Results:
MP-GRE and radial 3-D-GRE sequences had the least respiratory motion (P < 0.0001). Standard 3-D-GRE sequences displayed the lowest average score ratings in hepatic and pancreatic edge definition, hepatic vessel clarity and overall image quality. Radial 3-D-GRE sequences showed the highest scores ratings in overall image quality.
Conclusions:
Our preliminary results support the preference of fat-suppressed radial 3-D-GRE as the best post-contrast T1-weighted imaging approach for patients under the age of 5 years, when dynamic imaging is not essential.
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Computed Tomography (CT) scan:
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Computed Tomography
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