Related Experiment Video
Updated: May 1, 2026
Computerized Adaptive Testing System of Functional Assessment of Stroke
Published on: January 7, 2019
INCAT disability score: a critical analysis of its measurement properties
Ari Breiner1, Carolina Barnett, Vera Bril
1Division of Neurology, Department of Medicine, University of Toronto, 200 Elizabeth Street, Room 5EC-309, Toronto, Ontario, Canada, M5G 2C4.
Background:
The INCAT (Inflammatory Neuropathy Cause and Treatment) disability score is a measure of activity limitation. It is used frequently as a primary endpoint in inflammatory polyneuropathy clinical trials. A comprehensive critical analysis of its measurement properties has not been performed.
Methods:
Critical analysis of measurement properties.
Results:
The INCAT disability score was derived based on items from Guy's Neurological Disability Scale (GNDS), a disability measure intended for application in multiple sclerosis. Strengths of the INCAT score include evaluation of upper and lower limb dysfunction, ease of administration (feasibility), high face validity, and high reliability. Weaknesses of the scale include concerns about methodological quality of validation studies; failure to properly capture activity limitations due to proximal arm weakness, or fatigue; heavy individual item weighting; and poor sensitivity for detection of clinically important change.
Conclusions:
Although the INCAT scale has been an effective tool in inflammatory polyneuropathy studies, its limitations may warrant development of new scales.
More Related Videos
09:00Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education
Published on: August 16, 2024
11:35The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Related Concept Videos
01:29Intellectual Disability
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT