Hypertrophic pyloric stenosis in twins; genetic or environmental factors
H Ö Gezer1, P Oguzkurt, A Temiz
1Başkent University Faculty of Medicine, Department of Pediatric Surgery, Ankara, Turkey.
Abstract:
The etiology of infantile hypertrophic pyloric stenosis (IHPS) remains obscure. Over 120 years after the condition has become a clinical entity the debate whether the cause of IHPS is genetic, environmental or both, has not yet reached a final conclusion. Herein, we present a pair of monozygotic male twins with IHPS together with a review of the literature. We aimed to support genetic pre-disposition in the epidemiology of IHPS, adding a twin data to the literature and to review the associated articles about the pathogenesis and inheritance patterns.
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