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Sleep-disordered breathing in children with cardiomyopathy
Suhail Al-Saleh1, Paul F Kantor, Neil K Chadha
11 Division of Respiratory Medicine and.
Annals of the American Thoracic Society
|April 15, 2014
Summary
Sleep-disordered breathing is common in children with cardiomyopathy, with nearly half experiencing it. Central sleep apnea severity correlates with cardiac dysfunction in these pediatric patients.
Area of Science:
- Pediatric Cardiology
- Sleep Medicine
- Cardiovascular Research
Background:
- Cardiomyopathy in children is a rare condition with high mortality.
- Sleep-disordered breathing (SDB) is common, but its prevalence in pediatric cardiomyopathy is unknown.
Purpose of the Study:
- To determine the frequency and patterns of SDB in children with primary cardiomyopathy.
- To investigate the relationship between SDB and cardiac function in this population.
Main Methods:
- Prospective, uncontrolled case series involving 21 children with cardiomyopathy.
- Utilized polysomnography, sleep questionnaires, blood pressure monitoring, otolaryngological assessment, and echocardiography.
Main Results:
- 48% of patients had SDB; 24% had central sleep apnea (CSA).
- Left ventricular volumes were larger in children with CSA.
- CSA severity correlated with left ventricular end-diastolic and end-systolic volumes.
Conclusions:
- SDB is prevalent in pediatric cardiomyopathy, with CSA being a significant finding.
- Cardiac dysfunction severity is associated with CSA in these children.
- Further longitudinal studies are needed to understand sleep disorders' impact on pediatric cardiomyopathy.
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