Pain and bleeding associated with trephine biopsy

Area of Science:

• Medical Procedures
• Pain Management
• Surgical Complications

Background:

• Trephine biopsy is a common diagnostic procedure.
• Understanding patient pain experience and procedural complications is crucial for improving patient care.

Purpose of the Study:

• To quantify pain intensity and duration following trephine biopsy.
• To identify factors influencing the pain experience.
• To evaluate bleeding and infectious complications associated with the procedure.

Main Methods:

• 184 patients undergoing trephine biopsy were enrolled.
• Pain was assessed using the Numeric Rating Scale (NRS).
• Bleeding complications were graded, and infectious complications were monitored.

Main Results:

• 91% of patients experienced pain at the time of biopsy (T0), with a median NRS of 3.
• Median pain duration was 36 hours; 14 patients reported pain for over 7 days.
• Mild to moderate bleeding occurred in 64% of patients; no severe bleeding or infections were recorded. Two patients had secondary bleeding requiring hospitalization.
• Older age and higher BMI correlated with increased pain intensity and duration.

Conclusions:

• Trephine biopsy frequently results in moderate pain, necessitating effective pain management strategies.
• While bleeding complications are generally mild, vigilance for secondary bleeding is important.
• Patient age and BMI are factors that may influence post-biopsy pain.