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Conceptualizing Treatment Nonadherence in Patients with Bipolar Disorder and PTSD
CNS Spectrums
|April 15, 2014
Summary
Treatment nonadherence is a significant issue for patients with bipolar disorder and comorbid posttraumatic stress disorder (PTSD). Understanding factors contributing to noncompliance is crucial for improving patient outcomes in this complex population.
Area of Science:
- Psychiatry
- Clinical Psychology
- Pharmacology
Background:
- Treatment nonadherence is a concern in bipolar disorder (BD) and posttraumatic stress disorder (PTSD).
- Comorbidity of BD and PTSD is common and associated with a more severe illness course.
- Limited research exists on nonadherence factors in patients with comorbid BD-PTSD.
Purpose of the Study:
- To explore factors associated with treatment nonadherence in patients with comorbid bipolar disorder and posttraumatic stress disorder.
- To identify shared and unique predictors of noncompliance in this dual-diagnosis population.
Main Methods:
- Review of existing literature on nonadherence in primary BD and PTSD samples.
- Analysis of shared risk factors and population-specific predictors of noncompliance.
- Consideration of trauma-related meanings and patient-physician dynamics.
Main Results:
- Shared risk factors suggest a high likelihood of nonadherence in the BD-PTSD population.
- Early childhood trauma may influence noncompliance through trauma-related meanings of medical interactions.
- Patient-physician psychodynamics can contribute to nonadherence.
Conclusions:
- Clinicians must vigilantly monitor for nonadherence in BD-PTSD patients.
- Awareness of patient-physician psychodynamics is critical for managing noncompliance.
- Addressing trauma-related meanings may improve adherence in this population.
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