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Published on: July 14, 2023
The nasogastric tube syndrome in infants
Jeffrey Harmon1, Karthik Balakrishnan2, Alessandro de Alarcon3
1University of Cincinnati College of Medicine, Office of Student Affairs, Medical Sciences Building E-251, PO Box 670552, Cincinnati, OH 45267, United States.
Insights
Nasogastric tube syndrome in infants causes respiratory distress and postcricoid inflammation. Symptoms resolve quickly, differing from adult presentations, and should be considered in unexplained infant respiratory distress.
Area of Science:
- Pediatric Medicine
- Otolaryngology
- Gastroenterology
Background:
- Nasogastric tubes are common in infants for feeding and medication.
- Airway distress can occur in infants, with various potential causes.
- Nasogastric tube syndrome (NGTS) is recognized in adults but less understood in infants.
Purpose of the Study:
- To describe the presentation, clinical course, and endoscopic findings of NGTS in infants.
- To identify key differences between infant and adult NGTS.
- To raise awareness of NGTS as a differential diagnosis for infant respiratory distress.
Main Methods:
- Case series of three infants with NGTS.
- Clinical assessment and endoscopic examination.
- Literature review comparing infant and adult NGTS.
Main Results:
- Infant NGTS presented with significant respiratory distress and postcricoid inflammation.
- Vocal fold immobility was absent in these infant cases.
- Symptoms resolved rapidly, with a mean duration of 2±1 days.
Conclusions:
- Infant NGTS is characterized by respiratory distress and inflammation without vocal fold immobility.
- Recovery is typically faster in infants compared to adults.
- Consider NGTS in infants with unexplained respiratory distress, even without vocal fold immobility.
Abstract:
This series of three patients is the first description of the presentation, clinical course, and endoscopic findings of nasogastric tube-related airway distress, or nasogastric tube syndrome, in infants. We identify key differences in disease features from those described in adults, based on our literature review. Specifically, infant nasogastric tube syndrome presented as significant respiratory distress and postcricoid inflammation without vocal fold immobility. Symptoms resolved more quickly (mean±SD, 2±1 days) than reported in adults. We suggest that nasogastric tube syndrome should be considered in infants with otherwise unexplained respiratory distress, even in the absence of impaired vocal fold mobility.
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