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Updated: May 1, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Hybrid approach of percutaneous coronary intervention followed by minimally invasive valve operations
Orlando Santana1, Andrés M Pineda1, Mery Cortes-Bergoderi2
1Columbia University Division of Cardiology, Mount Sinai Medical Center, Miami Beach, Florida.
Insights
A hybrid approach combining percutaneous coronary intervention (PCI) and minimally invasive valve surgery offers excellent outcomes for patients with complex heart conditions. This strategy provides a viable alternative to traditional open-heart surgery for selected individuals.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Cardiac Valve Disease
Background:
- Combined coronary artery and valvular heart disease necessitates revascularization and valve repair/replacement.
- Traditional surgical approach involves median sternotomy for coronary artery bypass grafting (CABG) and valve operation.
- A hybrid strategy of percutaneous coronary intervention (PCI) followed by minimally invasive valve surgery may offer an alternative for select patients.
Purpose of the Study:
- To evaluate the outcomes of a hybrid approach combining PCI and minimally invasive valve operations.
- To assess the safety and efficacy of this approach in patients with concomitant coronary and valvular disease.
Main Methods:
- Retrospective evaluation of 222 patients undergoing PCI followed by minimally invasive valve operations (February 2009 - August 2013).
- Analysis included patient demographics, PCI details (vessel involvement), valve procedure types (primary/repeated, single/double valve), and operative outcomes.
- Follow-up data included repeat PCI, target-vessel revascularization, and survival rates.
Main Results:
- The study included 222 patients (mean age 74.6 years), with most undergoing single-vessel PCI and primary single-valve operations.
- Operative mortality was 3.6%.
- Survival rates at 1 and 4.5 years were 91.9% and 88.3%, respectively, with low rates of repeat PCI.
Conclusions:
- The hybrid approach of PCI followed by minimally invasive valve operations is feasible and effective in a heterogeneous patient group.
- This strategy demonstrates excellent short- and long-term outcomes, including survival.
- It represents a valuable treatment option for patients with combined coronary and valvular heart disease.
Background:
A subset of patients requiring coronary revascularization and valve operations may benefit from a hybrid approach of percutaneous coronary intervention (PCI) followed by a minimally invasive valve operation, rather than the standard combined median sternotomy coronary artery bypass grafting (CABG) and a valve operation. This study sought to evaluate the outcomes of this approach in a heterogeneous group of patients with concomitant coronary artery and valvular disease.
Methods:
We retrospectively evaluated 222 consecutive patients with coronary artery and valvular heart disease who underwent PCI followed by elective minimally invasive valve operations at our institution between February 2009 and August 2013.
Results:
A total of 136 men and 86 women were identified. The mean age was 74.6 ± 8.2 years, with 181 (81.5%) undergoing 1-vessel, 27 (12.2%) undergoing 2-vessel, and 14 (6.3%) undergoing 3-vessel PCI. Within a median of 38 days (interquartile range [IQR] 18-65 days), 182 (82%) patients underwent primary and 34 (15.3%) underwent repeated valve operations, which consisted of 185 (83.3%) single-valve and 37 (16.7%) double-valve procedures. Operative mortality occurred in 8 patients (3.6%). At a mean follow-up of 16.2 ± 12 months, 6 patients required PCI, with target-vessel revascularization performed in 4 patients (2.1%). Survival at 1 and 4.5 years was 91.9% and 88.3%, respectively.
Conclusions:
In a heterogeneous group of patients, a hybrid approach of PCI followed by minimally invasive valve operations in patients undergoing primary or repeated valve operations can be performed with excellent outcomes.
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