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Infective endocarditis due to Granulicatella adiacens: a case report and review

Kanne Padmaja1, Vemu Lakshmi, Sreevdya Subramanian

  • 1Nizam's Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India. paddu_naren@yahoo.co.in.

Journal of Infection in Developing Countries
|April 15, 2014
PubMed

Insights

Nutritionally variant Streptococci (NVS) cause severe infective endocarditis (IE) with high failure rates. This case report details successful combination therapy for NVS-IE in an elderly patient lacking typical risk factors.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Nutritionally variant Streptococci (NVS) are an uncommon cause of infective endocarditis (IE).
  • NVS-associated IE typically presents with higher rates of treatment failure and mortality compared to other Streptococcal IE.
  • Advances in automated blood culture systems have increased the detection of NVS, accounting for 5%-6% of IE cases.

Observation:

  • A case of IE caused by NVS is presented in an elderly female patient.
  • The patient had no identifiable predisposing risk factors for IE.
  • The diagnosis was confirmed through blood cultures.

Findings:

  • The patient was successfully treated with a combination antimicrobial therapy regimen.
  • This case highlights the potential for NVS-IE even in the absence of typical risk factors.
  • Successful treatment outcomes are achievable with appropriate antimicrobial strategies.

Implications:

  • This case underscores the importance of considering NVS in the differential diagnosis of IE, regardless of patient risk factors.
  • Combination antimicrobial therapy can be effective in managing NVS-associated IE.
  • Further research into optimal treatment strategies for NVS-IE is warranted to improve patient outcomes.

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