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Somatostatin: evidence for a role in thermal nociception

C R Morton1, W D Hutchison, I A Hendry

  • 1Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra.

Brain Research
|May 29, 1989
PubMed

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
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