Related Experiment Video
Updated: May 1, 2026

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
Published on: October 16, 2018
geiger v2.0: an expanded suite of methods for fitting macroevolutionary models to phylogenetic trees
Matthew W Pennell1, Jonathan M Eastman1, Graham J Slater1
1Department of Biological Sciences and Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, ID 83844, Department of Paleobiology, National Museum of Natural History, Smithsonian Institution, Washington, DC 20013, Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA, Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia and Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Phylogenetic comparative methods are crucial for evolutionary studies. The new geiger v2.0 R package offers efficient algorithms and new approaches for large-scale interspecific data analysis.
Area of Science:
- Evolutionary Biology
- Computational Biology
- Bioinformatics
Background:
- Phylogenetic comparative methods are vital for testing evolutionary hypotheses using interspecific data.
- The increasing scale and scope of available data present computational challenges for existing methods.
- Many current approaches are computationally infeasible or unsuitable for large datasets.
Purpose of the Study:
- To present geiger v2.0, a significantly updated version of the popular R package for phylogenetic comparative analysis.
- To provide more efficient algorithms for existing phylogenetic methods.
- To introduce novel approaches for handling heterogeneous models and data types in evolutionary analyses.
Main Methods:
- Reimplementation of existing phylogenetic comparative methods using optimized algorithms.
- Development of new computational approaches to accommodate large-scale interspecific datasets.
- Integration with the 'ape' R package for enhanced functionality.
Main Results:
- geiger v2.0 offers computationally feasible solutions for large phylogenetic datasets.
- The package provides enhanced capabilities for analyzing evolutionary hypotheses.
- New methods are introduced for accommodating diverse and complex evolutionary models and data.
Conclusions:
- geiger v2.0 is an essential tool for modern phylogenetic comparative analyses.
- The package addresses the limitations of previous methods when dealing with large datasets.
- It facilitates robust evolutionary research by providing efficient and flexible analytical tools.
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Phylogeny
Phylogenetic Trees
Phylogenetic Trees
Microbial Phylogeny
Evolution of Microbial Genome

