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Updated: May 1, 2026

Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization
Published on: December 3, 2020
Treatment of adult Class II division 2 patient with metal hypersensitivity
Seiji Haraguchi1, Takashi Yamashiro
1a Private Practice, Takarazuka, Japan.
Abstract:
This case report describes the orthodontic treatment of an adult female with an Angle Class II division 2 malocclusion with a severe deep bite and a congenitally missing lower incisor. The use of available orthodontic devices and materials was limited because the patient had metal allergies. Following a careful examination and case analysis, the preadjusted edgewise appliances and the microscrew implants were placed after the upper first premolars were extracted. After active treatment, a good facial profile and occlusion were achieved. These results have been maintained for 2 years following completion of the active treatment.
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