Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Aging of epidermis. I. Morphological changes and their quantitative analysis].

H Toyoshima

    Nihon Hifuka Gakkai Zasshi. the Japanese Journal of Dermatology
    |January 1, 1989
    PubMed
    Summary

    Sun exposure accelerates skin aging, causing smaller corneocytes and flattened epidermal ridges in older individuals. These changes are more pronounced in sun-exposed areas, indicating accelerated aging due to UV radiation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Long-term weight-change slope, weight fluctuation and risk of type 2 diabetes mellitus in middle-aged Japanese men and women: findings of Aichi Workers' Cohort Study.

    Nutrition & diabetes·2017
    Same author

    Association of coffee consumption with serum adiponectin, leptin, inflammation and metabolic markers in Japanese workers: a cross-sectional study.

    Nutrition & diabetes·2012
    Same author

    Sensitive pupil response of early-onset alzheimer's patients to a dilute mixture of cholinergic antagonist and α-Adrenergic stimulant.

    Environmental health and preventive medicine·2011
    Same author

    Influence of life-related factors and participation in health examination on mortality in a 4.5-year follow-up of a rural cohort.

    Environmental health and preventive medicine·2011
    Same author

    Accommodative load from handheld game consoles in kindergarten children.

    Environmental health and preventive medicine·2011
    Same author

    Smoking status, sports participation and mortality from coronary heart disease.

    Heart (British Cardiac Society)·2007

    Area of Science:

    • Dermatology
    • Histology
    • Aging Research

    Context:

    • Skin aging is a complex process influenced by intrinsic (chronological) and extrinsic factors.
    • Sun exposure (photoaging) is a major extrinsic factor contributing to visible skin aging.
    • Epidermal morphology provides key indicators of skin health and aging.

    Purpose:

    • To investigate the specific morphological changes in the epidermis resulting from aging and sun exposure.
    • To compare epidermal changes in sun-exposed versus sun-protected skin in both young and aged subjects.
    • To determine if sun exposure accelerates age-related epidermal alterations.

    Summary:

    • Light microscopy and micrometric techniques revealed that corneocytes in sun-exposed skin of young subjects were smaller than those in aged individuals.

    Related Experiment Videos

  • Epidermal rete ridges in sun-exposed skin of older subjects showed flattening and disappearance.
  • Epidermal thinning and flattening were more severe in sun-exposed areas compared to sun-protected areas of aged skin.

    • Impact:

    • The findings suggest that sun exposure significantly accelerates the morphological changes associated with skin aging.
    • This research highlights the detrimental effects of UV radiation on epidermal structure and function.
    • Understanding these changes can inform preventative strategies against premature skin aging.