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Updated: May 1, 2026

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Published on: August 6, 2015
Non-traumatic hypertrophic callus of the fibula mimicking osteosarcoma in osteogenesis imperfecta type V: a case
Arnold Radu1, Rene Epunza Kanza, Dezso Barabas
1Department of Radiology, McGill University Health Center (MUHC), Montreal, QC, H3G 1Y6, Canada.
Abstract:
We report a case of hyperplastic callus mimicking osteosarcoma in the fibula of a patient with osteogenesis imperfecta type V. Among the various imaging modalities, computed tomography was the most useful in distinguishing this rare process from a malignant entity. In addition, simple radiographs demonstrated the presence of characteristic "zebra lines", a manifestation of cyclic bisphosphonate therapy during childhood.
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