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Rescuing US biomedical research from its systemic flaws.

Bruce Alberts¹, Marc W Kirschner, Shirley Tilghman

¹Department of Biophysics and Biochemistry, University of California, San Francisco, CA 94158.

Proceedings of the National Academy of Sciences of the United States of America

|April 16, 2014

Summary

This summary is machine-generated.

The unsustainable growth in biomedical science creates a hypercompetitive environment, discouraging new talent and hindering experienced researchers. Rethinking the US biomedical research system is crucial for its long-term health.

Keywords:

federal funding graduate education peer review postdoctoral education

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Area of Science:

Biomedical Science
Research Ecosystems
Scientific Workforce

Background:

The assumption of perpetual rapid growth in biomedical science is flawed.
This has led to an unsustainable and hypercompetitive academic environment.
This system negatively impacts both prospective and established researchers.

Purpose of the Study:

To identify the detrimental effects of the current biomedical research system.
To advocate for a fundamental reevaluation of the US biomedical research ecosystem.
To address the unsustainable hypercompetitiveness within the field.

Main Methods:

Qualitative analysis of the current biomedical research landscape.
Examination of the impact of growth assumptions on the scientific workforce.
Review of systemic issues within the US biomedical research ecosystem.

Main Results:

The system discourages outstanding prospective students from entering the field.
Seasoned investigators face challenges in producing their best work.
The current trajectory poses a risk of long-term decline in biomedical science.

Conclusions:

Simplistic solutions are inadequate for addressing the systemic problems.
A fundamental rethinking of the US biomedical research ecosystem is necessary.
Addressing the unsustainable growth and hypercompetitiveness is vital for the future of biomedical science.