Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Drug Reactions01:27

Allergic Drug Reactions

1.6K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.6K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

280
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
280
Allergic Reactions02:06

Allergic Reactions

26.4K
Overview
26.4K
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

209
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
209
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

359
Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
359
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

2.4K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Climate Change and Asthma: Work-Related Risks and Planetary Implications.

Journal of occupational and environmental medicine·2025
Same author

Anti-IL-5/5Ra biologics improve work productivity and activity in severe asthma: a RAPSODI registry-based cohort study.

The Journal of asthma : official journal of the Association for the Care of Asthma·2023
Same author

Roadmap to improve regional care for patients with severe asthma.

Clinical and translational allergy·2021
Same author

Peanut components measured by ISAC: comparison with ImmunoCap and clinical relevance in peanut allergic children.

Clinical and molecular allergy : CMA·2021
Same author

Case-control study of patient characteristics, knowledge of the COVID-19 disease, risk behaviour and mental state in patients visiting an emergency room with COVID-19 symptoms in the Netherlands.

PloS one·2021
Same author

Describing fluctuating indoor aerosol dust measurements with application to house dust mite allergens.

Scientific reports·2020

Related Experiment Video

Updated: May 1, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.9K

Systematic review on cashew nut allergy.

J P M van der Valk1, A E J Dubois, R Gerth van Wijk

  • 1Erasmus MC, Rotterdam, The Netherlands.

Allergy
|April 17, 2014
PubMed
Summary
This summary is machine-generated.

Cashew nut allergy is an emerging health concern, with increasing prevalence and potential for severe reactions like anaphylaxis. Early recognition and awareness are crucial for managing this significant food allergy, particularly in children.

Keywords:
Anacardiaceaeallergycashewhypersensitivity

More Related Videos

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

25.3K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

15.9K

Related Experiment Videos

Last Updated: May 1, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.9K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

25.3K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

15.9K

Area of Science:

  • Allergy and Immunology
  • Clinical Medicine
  • Food Science

Background:

  • Cashew nut allergy is an increasingly recognized food allergy.
  • Consumption can lead to severe allergic reactions, including anaphylaxis.
  • This allergy is often underestimated, particularly in pediatric populations.

Purpose of the Study:

  • To systematically review the clinical aspects of cashew nut allergy.
  • To consolidate current knowledge on cashew nut allergy characteristics, prevalence, allergens, cross-reactivity, diagnosis, and management.
  • To enhance clinical recognition and awareness of cashew nut allergy.

Main Methods:

  • Systematic literature review.
  • Searched databases for articles on cashew nut allergy.
  • Included 40 relevant articles from an initial search of 255.

Main Results:

  • Evidence suggests an increasing prevalence of cashew nut allergy, though with low certainty.
  • Cashew nut allergens are potent, capable of causing severe reactions even in small amounts.
  • Cashew allergy represents a significant, underappreciated healthcare issue.

Conclusions:

  • Cashew nut allergy requires greater clinical attention and public awareness.
  • Understanding the clinical features is key to effective diagnosis and management.
  • Further research is needed to confirm prevalence trends and refine treatment strategies.