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Epidemiology of respiratory symptoms in children with Down syndrome: a nationwide prospective web-based

Ruud H J Verstegen, Roeland W N M van Hout, Esther de Vries1

  • 1Department of Pediatrics, Jeroen Bosch Hospital, PO Box 90153 's-Hertogenbosch 5200 ME, The Netherlands. e.d.vries@jbz.nl.

BMC Pediatrics
|April 17, 2014
PubMed

Insights

Children with Down syndrome experience frequent respiratory and ENT issues. This study tracks these symptoms over two years to understand their impact and healthcare needs.

Area of Science:

  • Pediatric Health
  • Genetics and Rare Diseases
  • Epidemiology

Background:

  • Children with Down syndrome frequently experience respiratory and ear-nose-throat (ENT) issues.
  • The prevalence and impact of these conditions, especially concerning comorbidities and aging, are not well understood.

Purpose of the Study:

  • To investigate the frequency and patterns of respiratory and ENT complaints in children with Down syndrome.
  • To explore the relationship between these symptoms, co-morbidities, and the aging process in this population.
  • To gain insights into healthcare utilization and parental work absence linked to these childhood illnesses.

Main Methods:

  • A prospective, web-based, parent-reported observational study design.
  • Involved parents of children aged 0-18 years with Down syndrome.
  • Utilized weekly questionnaires for symptom tracking and extended questionnaires for baseline and medical history data over two years, with comparison to a control group.

Main Results:

  • Data collection is ongoing; specific results are pending.
  • The study aims to establish epidemiological data on respiratory symptoms in children with Down syndrome.

Conclusions:

  • The study will yield crucial epidemiological data on respiratory symptoms in children with Down syndrome.
  • Findings will inform future research on treatment strategies and healthcare management.
  • Insights into healthcare usage and work absence will be provided.
Abstract

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