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Updated: May 1, 2026

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Geometrically enforced donor-facilitated dehydrocoupling leading to an isolable arsanylidine-phosphorane
Brian A Chalmers1, Michael Bühl, Kasun S Athukorala Arachchige
1EaStChem School of Chemistry, University of St. Andrews , Fife KY16 9ST, St. Andrews, U.K.
Abstract:
A proximate Lewis basic group facilitates the mild dehydrogenative P-As intramolecular coupling in the phosphine-arsine peri-substituted acenaphthene 3, affording thermally and hydrolytically stable arsanylidine-phosphorane 4 with a sterically accessible two-coordinate arsenic atom. The formation of 4 is thermoneutral due to the dehydrogenation being concerted with the donor coordination. Reaction of 4 with a limited amount of oxygen reveals arsinidene-like reactivity via formation of cyclooligoarsines, supporting the formulation of the bonding in 4 as base-stabilized arsinidene R3P→AsR.
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