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[Benign prostatic hyperplasia].

H W Bauer1, F Sudhoff, S Dressler

  • 1Urologischen Klinik des Klinikums Steglitz, Freien Universität Berlin, BRD.

Wiener Medizinische Wochenschrift (1946)
|May 31, 1989
PubMed
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Benign prostatic hyperplasia (BPH) affects over 40% of men over 50. Hormonal imbalances, specifically testosterone and estrogen metabolism, may contribute to its development, leading to various treatment options.

Area of Science:

  • Urology
  • Endocrinology
  • Andrology

Context:

  • Benign prostatic hyperplasia (BPH) is a common condition affecting over 40% of men aged 50 and above.
  • The pathogenesis of BPH is thought to involve disturbances in the metabolism of testosterone and estrogen within the prostate gland.
  • Current management strategies for symptomatic BPH include conservative therapy and surgical resection.

Purpose:

  • To explore the role of testosterone and estrogen metabolism in the development of benign prostatic hyperplasia.
  • To review the current therapeutic approaches for benign prostatic hyperplasia.
  • To highlight the frequent consequence of retrograde ejaculation following surgical treatment for BPH.

Summary:

  • Benign prostatic hyperplasia (BPH) is highly prevalent in aging men, with over 40% incidence in those over 50.

Related Experiment Videos

  • Evidence suggests that altered testosterone and estrogen metabolism within the prostate plays a role in BPH pathogenesis.
  • Surgical resection, a common treatment for BPH, frequently results in retrograde ejaculation.

    • Impact:

    • Understanding the hormonal underpinnings of BPH can lead to more targeted and effective therapeutic strategies.
    • Improved management of BPH may reduce the incidence of complications such as retrograde ejaculation.
    • This research contributes to the fields of urology and endocrinology by elucidating the complex factors involved in prostate health.