A randomized controlled trial comparing three single-incision minislings for stress urinary incontinence

Area of Science:

• Urology
• Gynecology
• Surgical Innovation

Background:

• Single-incision minislings (SIMS) are used for female urinary incontinence (UI).
• Existing efficacy data for SIMS show significant heterogeneity.
• The comparative long-term outcomes of different SIMS vaginal kits require investigation.

Purpose of the Study:

• To evaluate and compare the long-term efficacy of three distinct SIMS vaginal kits.
• To test the hypothesis that different SIMS kits yield varying long-term outcomes for UI treatment.

Main Methods:

• A multicenter randomized clinical trial involving 120 women with stress or mixed UI.
• Patients were treated with one of three SIMS: Ajust, MiniArc, or TVT Secur System.
• Follow-up was at least 24 months, assessing subjective cure rates, total failure, and reoperation rates.

Main Results:

• No statistically significant differences were observed in subjective cure rates (52.5%–65.0%) among the three SIMS groups.
• Total failure rates were also comparable across the groups (55.0%–67.5%).
• The proportion of patients requiring reoperation for UI did not differ significantly between the tested SIMS kits.

Conclusions:

• The long-term efficacy of single-incision minislings for female urinary incontinence is consistent across the evaluated vaginal kits.
• This suggests that the choice of vaginal kit may not significantly impact long-term UI treatment outcomes.