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Updated: May 1, 2026
07:24
Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
Published on: September 23, 2021
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A two-armed lanthanoid-chelating paramagnetic NMR probe linked to proteins via thioether linkages
Wei-Min Liu1, Simon P Skinner, Monika Timmer
1Leiden Institute of Chemistry, Leiden University, Post Office Box 9502, 2300 RA Leiden (The Netherlands).
Chemistry (Weinheim an Der Bergstrasse, Germany)
|April 17, 2014
Abstract:
Paramagnetic NMR probes provide valuable long-range structural information on proteins and protein complexes. A new, stable, two-armed lanthanoid probe is reported that can be attached to a protein site-specifically via chemically inert thioether linkages.
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