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Updated: May 1, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
Published on: October 3, 2025
Revitalizing personalized medicine: respecting biomolecular complexities beyond gene expression
D Jayachandran1, U Ramkrishna2, J Skiles3
1School of Chemical Engineering, Purdue University, West Lafayette, Indianapolis, USA.
Abstract:
Despite recent advancements in "omic" technologies, personalized medicine has not realized its fullest potential due to isolated and incomplete application of gene expression tools. In many instances, pharmacogenomics is being interchangeably used for personalized medicine, when actually it is one of the many facets of personalized medicine. Herein, we highlight key issues that are hampering the advancement of personalized medicine and highlight emerging predictive tools that can serve as a decision support mechanism for physicians to personalize treatments.
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