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Lorazepam-induced diplopia.

Jisha M Lucca1, Madhan Ramesh1, Gurumurthy Parthasarathi1

  • 1Department Pharmacy Practice, JSS College of Pharmacy, JSS University, Mysore, Karnataka, India.

Indian Journal of Pharmacology
|April 18, 2014
PubMed
Summary

Lorazepam, a common psychiatric medication, can rarely cause diplopia (double vision). This case highlights a potential, though infrequent, ocular side-effect of this benzodiazepine in patients with obsessive-compulsive disorder.

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Area of Science:

  • Ophthalmology and Neurology
  • Psychopharmacology

Background:

  • Diplopia, or double vision, is a common symptom with diverse neurological and ophthalmological origins.
  • Benzodiazepines are frequently prescribed in psychiatric practice, with lorazepam being a commonly used agent.
  • Ocular side-effects of benzodiazepines, particularly lorazepam, are seldom documented in medical literature.

Observation:

  • A patient newly diagnosed with obsessive-compulsive disorder was administered lorazepam.
  • The patient subsequently developed diplopia, a symptom not previously experienced.

Findings:

  • This case presents a rare instance of lorazepam-induced diplopia.
  • The exact frequency of this visual disturbance associated with lorazepam remains undetermined.

Implications:

  • Clinicians should consider lorazepam as a potential cause of diplopia, even if rare.
  • Further research is warranted to establish the incidence and underlying mechanisms of lorazepam-induced visual disturbances.