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Updated: May 1, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Neonatal meningitis complicating with pneumocephalus
Anita Kumari1, Satish C Agrawal1
1Department of Pediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Abstract:
Pneumocephalus is a rare condition characterized by the presence of gas within the cranial cavity. This gas may arise either from a trauma, a tumor, a surgical, or a diagnostic procedure or occasionally from an infection. Pneumocephalus as a complication of bacterial meningitis, in absence of trauma or a procedure, is extremely rare, particularly in a newborn. A case of pneumocephalus occurring in a baby, suffering from neonatal meningitis, acquired probably through unsafe cutting and tying of the cord, is reported here. Cutting, tying, and care of the umbilical cord is of utmost importance to prevent neonatal infection as the same is a potential cause of serious anaerobic infections, besides tetanus.
Insights
Pneumocephalus, a rare cranial gas accumulation, is exceptionally uncommon as a neonatal meningitis complication without trauma. This case highlights unsafe umbilical cord care as a potential cause of serious anaerobic infections in newborns.
Area of Science:
- Neurology
- Infectious Diseases
- Neonatal Care
Background:
- Pneumocephalus, the presence of intracranial gas, typically results from trauma, surgery, or tumors.
- While infections can cause pneumocephalus, it is exceedingly rare as a complication of bacterial meningitis, especially in neonates.
- Neonatal meningitis poses significant risks, and potential sources of infection require careful consideration.
Observation:
- A newborn presented with neonatal meningitis.
- The infant also developed pneumocephalus.
- No history of trauma or surgical/diagnostic procedures was reported.
Findings:
- The case suggests a potential link between unsafe umbilical cord management and the development of neonatal meningitis with subsequent pneumocephalus.
- This highlights the risk of anaerobic infections, including tetanus, arising from improper cord care.
- Pneumocephalus in this context is an extremely rare manifestation.
Implications:
- Emphasizes the critical importance of sterile and safe umbilical cord cutting and tying techniques in preventing neonatal infections.
- Underscores the need for vigilance in diagnosing rare complications like pneumocephalus in neonates with meningitis.
- Suggests that umbilical cord care practices are paramount for neonatal sepsis prevention.
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