Related Experiment Video
Updated: May 1, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Parkinson's disease and carotid intima-media thickness
Unlabelled:
Reports about the impact of cerebrovascular disease (CVD) on clinical status in Parkinson's disease (PD) are rather controversial. There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis.
Aim:
This study was done to investigate the carotid IMT between PD patients and controls.
Material And Methods:
A total of 54 PD patients and 50 controls were examined. The duration of Parkinson's disease, the severity of Parkinson's disease (the Hoehn-Yahr stage) and carotid IMT were examined.
Results:
The mean Hoehn and Yahr stage was 2.78 (range 2-4). Duration of disease had a mean of 7.59 +/- 0.85 years. The left CCA mean IMT was 0.900 +/- 0.147 in Parkinson group and 0.828 +/- 0.118 in control group (p = 0.007). The right CCA mean IMT was 0.891 +/- 0.176 mm in the Parkinson group and 0.860 +/- 0.164 in control group (p = 0.360). No relationship between the Hoehn and Yahr stages or the duration of PD with the IMT were found by the Pearson's correlation test.
Conclusions:
The carotid IMT was higher in PD patients than in controls.
More Related Videos
06:04Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
09:36A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
Published on: August 12, 2025
Related Concept Videos
Parkinson Disease l: Introduction
Peripheral Artery Disease I: Introduction
Parkinson Disease ll: Pathophysiology
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...