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Thyroid dysfunction and ischemic heart disease--clinical correlations, progressive implications and impact on the

Daniela Maria Tănase, Simona Daniela Ionescu, Anca Ouatu

    Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
    |April 19, 2014
    PubMed

    Insights

    Thyroid dysfunction significantly impacts ischemic heart disease risk and progression. Evaluating thyroid function is crucial for managing cardiovascular health, especially in at-risk patients.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Internal Medicine

    Background:

    • Thyroid dysfunctions are linked to various cardiovascular issues, including heart dysfunction and hypertension.
    • Clinically significant hyperthyroidism and hypothyroidism can affect patients with existing ischemic heart disease.

    Purpose of the Study:

    • To investigate the risk, evolution, and prognosis of ischemic heart disease across the spectrum of thyroid dysfunctions.

    Main Methods:

    • A study group of 791 subjects with heart disorders and controlled thyroid status was established.
    • Participants were divided into five groups based on thyroid hormone levels.
    • Cardiovascular and thyroid status were evaluated at 6 and 12 months.

    Main Results:

    • 49% of the control group developed ischemic heart disease; risk factors included high heart rate, age over 60, female sex, and elevated triglycerides.
    • Overt hyperthyroidism showed 46.1% incidence of ischemic heart disease, with similar risk factors plus high LDL-cholesterol.
    • Overt hypothyroidism showed 53.3% incidence, with risk factors including high heart rate, age over 60, elevated triglycerides, LDL-cholesterol, and hypertension.

    Conclusions:

    • Thyroid dysfunction plays a key role in cardiovascular regulation and the progression of ischemic heart disease.
    • Thyroid function evaluation is essential for patients with heart disease, particularly those at risk for ischemic heart disease.
    Abstract

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