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The frequency and risk factors of allergy and asthma in children with autism--case-control study

Dorota Mrozek-Budzyn, Renata Majewska, Agnieszka Kiełyka

    Przeglad Epidemiologiczny
    |April 19, 2014
    PubMed

    Insights

    Children with autism experience asthma and allergies at rates similar to neurotypical children. Parental allergy, particularly the father's, is a risk factor for allergies in autistic children.

    Area of Science:

    • Pediatric Allergy
    • Autism Spectrum Disorder Research
    • Childhood Comorbidities

    Background:

    • Autism Spectrum Disorder (ASD) evolution can be influenced by co-occurring conditions.
    • Allergic diseases are highly prevalent in children and may impact ASD symptoms.
    • Understanding the relationship between allergies and autism is crucial for comprehensive care.

    Purpose of the Study:

    • To compare the frequency of asthma and allergic diseases in children with autism versus controls.
    • To identify risk factors for allergic diseases and asthma in both groups.

    Main Methods:

    • A case-control study involving 96 children with autism and 192 matched controls.
    • Analysis conducted separately for autism and control groups to enable comparison.
    • Matched controls by year of birth, gender, and physician's practice.

    Main Results:

    • No statistically significant difference in asthma or allergic disease frequency between children with autism and controls.
    • Asthma affected 5.2% of children with autism and 4.7% of controls; allergies affected 25.0% and 21.9%, respectively.
    • Father's history of allergy/asthma was a risk factor for allergies in children with autism.

    Conclusions:

    • Children with autism exhibit similar rates of asthma and allergies compared to children without autism.
    • Allergic diseases in the father represent a significant risk factor for developing allergies in children with autism.
    Abstract

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