Related Experiment Video
Updated: May 1, 2026
Three-Dimensional In Vitro Biomimetic Model of Neuroblastoma Using Collagen-Based Scaffolds
Published on: July 9, 2021
Vascular skeletalization ---- a new concept to improve the resection rate in childhood neuroblastoma
1Department of General Surgery, General Hospital of People's Liberation Army, Beijing, Fuxing Route 28th 100853, China - Liu2036@163.com.
Aim:
The surgical resection rate in childhood neuroblastoma (Stage Ⅲ and Ⅳ) is relatively low and influences the prognosis greatly. This study analyzes the surgical resection rate of stage I neuroblastoma in children.
Methods:
The tumors are shrunk with preoperative chemotherapy and surgical resection in the iliac vessels is performed to skeletalize the large retroperitoneal vascular. Using this method, 22 cases of childhood neuroblastoma received resections and the outcomes were analyzed.
Results:
The tumors were completely removed in 21 out of the 22 cases (95.45% in total). There were no serious complications and perioperative deaths.
Conclusions:
Using proper surgical methods and skeletalizing the large retroperitoneal vessels significantly increases the resection rate.
