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[Aortic valve replacement after percutaneous transcatheter aortic valvuloplasty for severe aortic stenosis]
Tetsuro Uchida1, Cholsu Kim, Yoshiyuki Maekawa
1econd Department of Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.
Insights
Surgical aortic valve replacement (AVR) after percutaneous transcatheter aortic valvuloplasty (PTAV) is safe and effective for high-risk patients with severe aortic stenosis. PTAV serves as a valuable bridge to AVR or palliative treatment.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Context:
- Severe aortic stenosis (AS) often necessitates aortic valve replacement (AVR).
- Elderly patients with comorbidities may be unsuitable for direct AVR.
- Percutaneous transcatheter aortic valvuloplasty (PTAV) offers palliative or bridge therapy for AS.
Purpose:
- To evaluate the effectiveness and clinical outcomes of surgical AVR following PTAV.
- To assess the safety and feasibility of AVR in patients previously treated with PTAV.
Summary:
- Five high-risk patients with severe AS underwent AVR after PTAV between 2010 and the study period.
- PTAV was used as a bridge to AVR in two patients, for restenosis in two, and prior to non-cardiac surgery in one.
- All patients experienced improved cardiac hemodynamics post-AVR, with no operative mortality and uneventful recovery.
Impact:
- Surgical AVR can be safely performed in high-risk patients with a history of PTAV.
- PTAV is a viable option for palliation or as a bridge to definitive AVR in patients unsuitable for initial surgery.
Background:
Aortic valve replacement( AVR) is a definitive treatment in patients with severely calcified aortic stenosis (AS). However, elderly patients with multiple comorbidities are considered to be unsuitable for AVR. Percutaneous transcatheter aortic valvuloplasty( PTAV) has been performed as a palliative option to relieve symptoms or to be a bridge use toward definitive therapy. This study aimed to examine the effectiveness and clinical outcome of surgical AVR subsequent to PTAV.
Patients And Methods:
Since 2010, 5 symptomatic patients have undergone AVR after PTAV in our institution. PTAV was performed as a bridge to definitive AVR in 2 patients. Other 2 patients developed symptomatic aortic valve restenosis during a follow-up, and required AVR. In the last patient,AVR was carried out after successful noncardiac surgery subsequent to PTAV.
Results:
AVR improved cardiac hemodynamics in all patients. There was no operative death. Postoperative course was uneventful and all patients were discharged on foot except for 1 patient in whom metastatic liver tumor from advanced gastric cancer was noted.
Conclusion:
AVR might be performed safely even in high-risk patients with the history of PTAV. PTAV is useful as a palliation or a bridge to definitive therapy for treatment of patients with severe AS unsuitable for surgery.
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