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Complete Genome Sequence of a Virulent Streptococcus agalactiae Strain, 138P, Isolated from Diseased Nile Tilapia
Julia W Pridgeon1, Dunhua Zhang
1Aquatic Animal Health Research Unit, USDA, ARS, Auburn, Alabama, USA.
Abstract:
Streptococcus agalactiae strain 138P was isolated from the kidney of diseased Nile tilapia in Idaho during a 2007 streptococcal disease outbreak. The full genome sequence of S. agalactiae 138P is 1,838,701 bp. The availability of this genome will allow comparative genomics analysis to identify genes for antigen discovery and vaccine development.
Insights
Streptococcus agalactiae strain 138P was identified from diseased Nile tilapia. Its genome sequencing aids in discovering antigens and developing vaccines for streptococcal disease.
Area of Science:
- Microbiology
- Genomics
- Veterinary Science
Background:
- Streptococcus agalactiae causes disease in Nile tilapia.
- An outbreak in 2007 led to the isolation of strain 138P from diseased fish kidneys.
Purpose of the Study:
- To perform whole-genome sequencing of Streptococcus agalactiae strain 138P.
- To enable comparative genomics for antigen discovery and vaccine development.
Main Methods:
- Isolation of Streptococcus agalactiae strain 138P from diseased Nile tilapia.
- Whole-genome sequencing of the isolated strain.
Main Results:
- The complete genome sequence of S. agalactiae 138P was determined to be 1,838,701 base pairs.
- The genome sequence provides a foundation for further analysis.
Conclusions:
- The genome sequence of S. agalactiae 138P is a valuable resource.
- This resource will facilitate research into antigen discovery and vaccine development for streptococcal infections in tilapia.
